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293407

Sigma-Aldrich

2-Quinoxalinecarboxylic acid

97%

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About This Item

Empirical Formula (Hill Notation):
C9H6N2O2
CAS Number:
Molecular Weight:
174.16
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

mp

208 °C (dec.) (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1cnc2ccccc2n1

InChI

1S/C9H6N2O2/c12-9(13)8-5-10-6-3-1-2-4-7(6)11-8/h1-5H,(H,12,13)

InChI key

UPUZGXILYFKSGE-UHFFFAOYSA-N

General description

Linear and Freundlich adsorption isotherm coefficient of 2-quinoxalinecarboxylic acid has been evaluated.

Application

2-Quinoxalinecarboxylic acid has been used in the preparation of:
  • N-(2-quinoxaloyl)-α-amino acids
  • bisquinoxaloyl (bisquinoxalinecarbonyl) derivatives

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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N Prabavathi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 92, 325-335 (2012-03-27)
The FTIR and FT-Raman spectra of 2-quinoxaline carboxylic acid (2-QCA) has been recorded in the region 4000-450 and 4000-100 cm(-1), respectively. The conformational analysis, optimized geometry, frequency and intensity of the vibrational bands of 2-QCA were obtained by the density
M D Rose et al.
Food additives and contaminants, 12(2), 177-183 (1995-03-01)
A method for the determination of residues of quinoxaline-2-carboxylic acid (QCA), the major metabolite of carbadox, in pig kidney has been developed. Tissue samples were subjected to alkaline hydrolysis, liquid-liquid extractions, ion-exchange chromatography and further extraction to concentrate the analyte
D Peng et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 28(11), 1524-1533 (2011-08-11)
The feed drug additive carbadox is a suspected carcinogen and mutagen. To monitor effectively residues of carbadox in the edible tissues of food-producing animals, an indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) to detect quinoxaline-2-carboxylic acid, the marker residue of carbadox
Lingli Huang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 874(1-2), 7-14 (2008-10-08)
Cyadox (CYX) is an antimicrobial growth-promoter of the quinoxalines. It is highly effective on improving growth and feed conversion of chicken with little toxicity. For food safety concerns, HPLC-UV methods were developed for the sequential determination of CYX and its
Joshua A Hagen et al.
Sensors (Basel, Switzerland), 11(7), 6645-6655 (2011-12-14)
Zinc oxide field effect transistors (ZnO-FET), covalently functionalized with single stranded DNA aptamers, provide a highly selective platform for label-free small molecule sensing. The nanostructured surface morphology of ZnO provides high sensitivity and room temperature deposition allows for a wide

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