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Merck

Effectiveness of hand hygiene for removal of Clostridium difficile spores from hands.

Infection control and hospital epidemiology (2013-02-08)
Sarah L Edmonds, Carrie Zapka, Douglas Kasper, Robert Gerber, Robert McCormack, David Macinga, Stuart Johnson, Susan Sambol, Christopher Fricker, James Arbogast, Dale N Gerding
ABSTRACT

This study determined whether surrogate organisms can predict activity against Clostridium difficile spores and compared the efficacy of hand hygiene preparations against C. difficile. Our data suggest that surrogate organisms were not predictive of C. difficile spore removal. Four preparations were significantly more effective than tap water at removing C. difficile.

MATERIALI
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Sigma-Aldrich
ipoclorito di sodio, reagent grade, available chlorine 4.00-4.99 %
Sigma-Aldrich
ipoclorito di sodio, reagent grade, available chlorine 10-15 %
Sigma-Aldrich
ipoclorito di sodio, 6-14% active chlorine basis
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Triclosan, 97.0-103.0% (active substance, GC)
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Peracetic acid solution, 36-40 wt. % in acetic acid
Sigma-Aldrich
ipoclorito di sodio, purum, ~10% (RT)