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Merck

Natural products in parallel synthesis: triazole libraries of nonactic acid.

Bioorganic & medicinal chemistry letters (2008-07-01)
Sarah B Luesse, Gregg Wells, Abhijit Nayek, Adrienne E Smith, Brian R Kusche, Stephen C Bergmeier, Mark C McMills, Nigel D Priestley, Dennis L Wright
ABSTRACT

The synthesis of a library of nonactic acid-derived triazoloamide derivatives and their evaluation as antimicrobial agents is described.

MATERIALI
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Sigma-Aldrich
Nonactin, from Streptomyces griseus, ≥98.0% (Total homologs, HPLC)
Sigma-Aldrich
Ammonium ionophore I, Selectophore, function tested, ≥98.0% ((Total homologs), HPLC)