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1406005

USP

Methazolamide

Name: Methazolamide
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

5-Acetylimino-4-methyl-·2-1,3,4-thiadiazoline-2-sulfonamide, N-(4-Methyl-2-sulfamoyl-Δ²-1,3,4-thiadiazolin-5-ylidene) acetamide, L 584601, N-[5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide

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Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₅H₈N₄O₃S₂

Numero CAS:

554-57-4

Peso molecolare:

236.27

NACRES:

NA.24

PubChem Substance ID:

329750392

UNSPSC Code:

41116107

MDL number:

MFCD00083416

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Proprietà

grade

pharmaceutical primary standard

agency

USP

API family

methazolamide

manufacturer/tradename

USP

mp

208 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CN1N=C(S\C1=N\C(C)=O)S(N)(=O)=O

InChI

1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+

InChI key

FLOSMHQXBMRNHR-QPJJXVBHSA-N

Gene Information

human ... CA1(759), CA2(760), CA4(762), CA7(766)

Descrizione

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Methazolamide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Methazolamide Tablets

Biochem/physiol Actions

Cell-permeable and potent carbonic anhydrase (CA) inhibitor

Methazolamide is a cell-permeable and potent carbonic anhydrase (CA) inhibitor that is used in the treatment of glaucoma. Methazolamide is an insulin sensitizer that reduces hepatic glucose generation in animal models.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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Questo articolo	SML0720	PHR3202	1005004
USP 1406005 Methazolamide	Sigma-Aldrich SML0720 Methazolamide	Supelco PHR3202 Methazolamide	USP 1005004 Acetazolamide
manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename -	manufacturer/tradename USP
grade pharmaceutical primary standard	grade -	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard
format neat	format -	format -	format neat
application(s) pharmaceutical (small molecule)	application(s) -	application(s) pharmaceutical	application(s) pharmaceutical (small molecule)
Gene Information human ... CA1(759), CA2(760), CA4(762), CA7(766)	Gene Information human ... CA1(759), CA2(760), CA4(762), CA7(766)	Gene Information -	Gene Information human ... CA1(759), CA12(771), CA2(760), CA4(762)
mp 208 °C (dec.) (lit.)	mp 208 °C (dec.) (lit.)	mp 208 °C (dec.) (lit.)	mp -

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pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302 + H312 + H332,H351

pcodes

P201 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c