1226003

Doxiciclina

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: Doxycycline hydrochloride hemiethanolate hemihydrate
• Formula empirica (notazione di Hill): C₂₂H₂₄N₂O₈ · HCl · 0.5H₂O · 0.5C₂H₆O
• Numero CAS: 24390-14-5
• Peso molecolare: 512.94
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749678
• MDL number: MFCD07357237
• Beilstein/REAXYS Number: 5702728

Proprietà

• grade: pharmaceutical primary standard
• agency: USP
• API family: doxycycline
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58
• InChI: 1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10?,14?,15-,17-,22-;;;;/m00..../s1
• InChI key: HALQELOKLVRWRI-ZVACAFRPSA-N

Descrizione

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Doxycycline hyclate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Doxycycline Hyclate Tablets
• Doxycycline Hyclate Capsules
• Doxycycline Hyclate Delayed-Release Tablets
• Doxycycline Hyclate Delayed-Release Capsules
• Doxycycline Tablets
• Doxycycline Capsules

Biochem/physiol Actions

Modalità d′azione: La doxiciclina iclato inibisce la risposta infiammatoria alla Spirochete Borrelia burgdorferi responsabile della malattia di Lyme.

Spettro di azione: Efficace nei confronti di inibitori ad ampio spettro delle metalloproteinasi della matrice in vivo.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informazioni sulla sicurezza

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335,H361fd,H412
• pcodes: P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe di stoccaggio: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable