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1201002

USP

17α-Dihydroequilin

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

17alpha-Dihydroequilin, α-Equilol, Estra-1,3,5(10),7-tetraene-3,17α-diol

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About This Item

Formula empirica (notazione di Hill):
C18H22O2
Numero CAS:
Peso molecolare:
270.37
Numero MDL:
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

equilin

Produttore/marchio commerciale

USP

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

OC1C2(C(CC1)C3=CCc4c(ccc(c4)O)C3CC2)C

InChI

1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3-5,10,14,16-17,19-20H,2,6-9H2,1H3
NLLMJANWPUQQTA-UHFFFAOYSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

17α-Dihydroequilin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Conjugated Estrogens
  • Conjugated Estrogens Tablets

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

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Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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J G Wilcox et al.
Fertility and sterility, 66(5), 748-752 (1996-11-01)
To determine the independent biologic effects of 17 alpha-dihydroequilin sulfate. Prospective randomized study. University of Southern California Medical Center. Twenty-one postmenopausal women, mean age 50 +/- 2 (+/-SEM) years, and mean body mass index 27 +/- 2. Women were randomized
S A Washburn et al.
American journal of obstetrics and gynecology, 169(2 Pt 1), 251-254 (1993-08-01)
Our purpose was to determine the effect of Premarin (conjugated estrogens) and three of its component estrogens on uterine weight and plasma cholesterol concentrations in surgically menopausal female rats. A randomized trial of Premarin and three component estrogens--estrone sulfate, 17
B R Bhavnani et al.
The Journal of clinical endocrinology and metabolism, 77(5), 1269-1274 (1993-11-01)
The constant infusion of [3H]equilin sulfate ([3H]EqS) was used to estimate the MCR of equilin sulfate (EqS) and to measure the conversion of this estrogen to equilin (Eq), equilenin (Eqn), equilenin sulfate (EqnS), 17 beta-dihydroequilin (17 beta-Eq), 17 beta-dihydroequilin sulfate
B R Bhavnani et al.
Journal of the Society for Gynecologic Investigation, 7(3), 175-183 (2000-06-24)
To compare the pharmacokinetics and relative bioavailabilities of key estrogen components of Premarin (Wyeth-Ayerst, Canada) with those of a generic conjugated estrogen preparation, C.E.S. (synthetic mixture of estrogens; ICN, Montreal, Canada) in healthy postmenopausal women. We conducted a randomized, single-dose
S J Foster et al.
The Journal of steroid biochemistry and molecular biology, 82(4-5), 401-411 (2003-02-19)
In on-going studies of 'classical' and ring B-unsaturated oestrogens in equine pregnancy, the products of metabolism of [2,2,4,6,6-2H(5)]-testosterone and [16,16,17-2H(3)]-5,7-androstadiene-3 beta,17 beta-diol with equine placental subcellular preparations and allantochorionic villi have been identified. Using mixtures of unlabelled and [2H]-labelled steroid

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