1148089

Collagenasi

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: Clostridiopeptidasi A
• Numero CAS: 9001-12-1
• UNSPSC Code: 41116107
• NACRES: NA.24
• Numero CE: 3.4.24.3 (BRENDA, IUBMB)
• MDL number: MFCD00130830
• eCl@ss: 25140904

Proprietà

• grade: pharmaceutical primary standard
• agency: USP
• form: liquid
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical
• format: neat

Descrizione

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Collagenase I is an enzyme that breaks down collagen, a primary structural protein in connective tissues. It is used in various medical and research applications, including tissue dissociation and wound debridement.​

The USP Collagenase I standard provides a benchmark for the activity and purity of collagenase I, ensuring its efficacy and safety in therapeutic and laboratory settings.

The USP biologics proteins category provides critical standards and reference materials necessary for the development and manufacturing of therapeutic proteins. These proteins, which can be naturally derived or genetically engineered, are essential in treating various diseases and conditions, ensuring that they meet quality, safety, and efficacy standards.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Biochem/physiol Actions

La collagenasi è attivata da quattro grammi atomo di calcio per mole di enzima. È inibita da etilen-glicol-bis(beta-amminoetil etere) - acido N, N, N′,N′-tetraacetico, beta-mercaptoetanolo, glutatione, acido tioglicolico e 8-idrossichinolina.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

This product is part of the USP Biologics program.

Una unità di digestione del collagene (CDU) libera peptidi da collagene proveniente da tendine d′Achille bovino equivalente in colore ninidrina a 1,0 μmole di leucina in 5 ore a pH 7,4 a 37 °C in presenza di ioni calcio. Una unità di idrolisi FALGPA idrolizza 1,0 μmole di furilacriloil-Leu-Gly-Pro-Ala per minuto a 25 °C. Una unità di proteasi neutra idrolizza caseina e produce colore equivalente a 1,0 μmole di tirosina per 5 ore a pH 7,5 a 37 °C. Una unità di clostripaina idrolizza 1,0 μmole of BAEE per minuto a pH 7,6 a 25 °C in presenza di DTT.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Parola di avvertenza: Danger
• Codici di pericolo: H334
• Avvertenze di sicurezza: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Classe di stoccaggio: 12 - Non Combustible Liquids
• Che succede?: WGK 1
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable