1012101

Adenine

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 6-Aminopurine, Vitamin B₄
• Formula empirica (notazione di Hill): C₅H₅N₅
• Numero CAS: 73-24-5
• Peso molecolare: 135.13
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329748937
• MDL number: MFCD00041790
• Beilstein/REAXYS Number: 5777

Proprietà

• grade: pharmaceutical primary standard
• agency: USP
• API family: adenine
• form: powder
• manufacturer/tradename: USP
• mp: >360 °C (lit.)
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Nc1ncnc2[nH]cnc12
• InChI: 1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)
• InChI key: GFFGJBXGBJISGV-UHFFFAOYSA-N

Descrizione

General description

Adenine is a purine nucleobase that is a fundamental component of nucleic acids, including DNA and RNA. In the context of oligonucleotide synthesis, adenine is incorporated into synthetic DNA or RNA sequences. The USP Adenine standard ensures the purity and consistency of adenine used in the synthesis of oligonucleotides for research, therapeutic, and diagnostic purposes.

The USP biologics oligonucleotides category includes a variety of synthetic nucleic acid sequences that are essential in research, diagnostics, and therapeutic applications. These oligonucleotides play crucial roles in molecular biology, including gene expression regulation, antisense therapy, and RNA interference. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of oligonucleotide products throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Adenine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Anticoagulant Citrate Phosphate Dextrose Adenine Solution
• Adenosine
• S-Adenosyl-l-methionine 1
• 4-Butanedisulfonate

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

This product is part of USP Biologics Program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Informazioni sulla sicurezza

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral
• Classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects