T3757
Sinonimo/i:
4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid, Arotinoid acid
| Voi/SKU | Disponibilità | Prezzo |
|---|---|---|
10 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 436.00 |
TTNPB,
ethanol: soluble 10 mM, DMSO: soluble 25 mM, chloroform/methanol: soluble 9.80-10.20 mg/mL, clear, colorless to light yellow
−20°C
C\C(=C/c1ccc(cc1)C(O)=O)c2ccc3c(c2)C(C)(C)CCC3(C)C
1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
FOIVPCKZDPCJJY-JQIJEIRASA-N
human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)
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Questo articolo | |||
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| description - | description A synthetic stilbene analog of retinoic acid that acts as a potent retinoic acid receptor (RAR) agonist (EC50 = 21 nM, 4.0 nM, and 2.4 nM for RARα, RARβ, and RARγ, respectively). | description - | description - |
| Quality Level 200 | Quality Level 100 | Quality Level - | Quality Level - |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. - | storage temp. - |
| solubility ethanol: soluble 10 mM, DMSO: soluble 25 mM, chloroform/methanol: soluble 9.80-10.20 mg/mL, clear, colorless to light yellow | solubility DMSO: 5 mg/mL | solubility - | solubility - |
| Gene Information human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258) | Gene Information - | Gene Information - | Gene Information - |
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Danger
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
Respiratory system
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK 3
Not applicable
Not applicable
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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The solution stability has not been determined for this product. One paper reports storage of 1 mM stock solutions of TTNPB in 95 % ethanol at - 80 deg C, protected from light in opaque containers or foil wrap.
Le, X.-F., et al., Regulation of AML2/CBFA3 in Hematopoietic Cells through the Retinoic Acid Receptor -Dependent Signaling Pathway. J. Biol. Chem., 274(31), 21651-21658 (1999).
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What other solvent is TTNPB, product T3757, soluble in besides the solvents given in the product listing - chloroform, ethanol and DMSO?
TTNPB, product T3757, is also soluble in dimethylformamide purged with an inert gas.
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How should a solution of TTNPB, product T3757, be stored?
Following reconstitution a solution of TTNPB, T3757, should be stored at 4° C.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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