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T3396

Sigma-Aldrich

Tetraglycol

BioXtra

Sinonimo/i:

Glycofurol, Tetrahydrofurfuryl alcohol polyethyleneglycol ether

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About This Item

Numero CAS:
31692-85-0
Numero MDL:
MFCD00801146
Codice UNSPSC:
12352201
NACRES:
NA.25

Descrizione

non-ionic

Nome Commerciale

BioXtra

Forma fisica

liquid (clear)

Impurezze

<0.5% water (Coulometric)
<5 ppm heavy metal

Colore

colorless to light yellow

Punto di fusione

≤ -100  °C

Solubilità

water: soluble 3420 g/L

Densità

1.09 g/mL at 25 °C (lit.)

InChI

1S/C7H14O3/c8-3-5-9-6-7-2-1-4-10-7/h7-8H,1-6H2
CTPDSKVQLSDPLC-UHFFFAOYSA-N

Categorie correlate

Applicazioni

Tetraglycol has been used:
  • to dilute DiI (1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate) for injecting fertilized chicken eggs for DiI labeling
  • to dilute DiI (1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate) and diO (3,3′-dioctadecyloxacarbocyanine perchlorate) for dye/virus injections
  • to dilute poly (lactide-co-glycolide) (PLGA) to prepare PLGA/F127 solution

Used as solvent to dissolve water-insoluble compounds.

Azioni biochim/fisiol

Liquid glycofurol can readily transform into gel systems with excellent elasticity due to which, it can be used as a medium to dissolve water-insoluble drugs.

Caratteristiche e vantaggi

Efficient solubilizer for glibenclamide (GBD)

Avvertenza

Do not confuse with tetraethylene glycol, which is also sometimes called tetraglycol.

Altre note

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H319

Classi di pericolo

Eye Irrit. 2

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

275.0 °F - closed cup

Punto d’infiammabilità (°C)

135 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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X F Zhang et al.
Materials science & engineering. C, Materials for biological applications, 32(6), 1654-1663 (2012-08-01)
Poly (lactide-co-glycolide) (PLGA) - Pluronic F127 - glass composites have demonstrated excellent potential, from the perspective of controlled mechanical properties and cytocompatibility, for peripheral nerve regeneration. In addition to controlling the mechanical properties and cytotoxicity for such composite devices, the
Saly Galal et al.
Acta pharmaceutica (Zagreb, Croatia), 53(1), 57-64 (2004-02-11)
The ability of liquid and semi-solid matrix (SSM) filling capsule technology to improve the dissolution rate of glibenclamide (GBD) was investigated. Semiquantitative estimation of GBD solubility in various vehicles was carried out. Tetraglycol was found to be the most efficient
Nahla Salah Barakat
AAPS PharmSciTech, 11(3), 1138-1146 (2010-07-24)
In view of the good skin tolerability, glycofurol was used as a vehicle-based gel, and its effect in the topical penetration of Naproxen (NAP) was investigated. The aims of this study were to develop a suitable gel with bioadhesive property
S Kehoe et al.
Journal of the mechanical behavior of biomedical materials, 14, 180-185 (2012-10-03)
PLGA/pluronic F127 based nerve guidance conduits (NGCs) for peripheral nerve regeneration offer excellent potential for clinical use. To date, little emphasis has been directed towards the effect of pluronic F127 on their subsequent mechanical properties as a function of degradation

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