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T122

Telenzepine dihydrochloride hydrate

Name: Telenzepine dihydrochloride hydrate
Brand: SIGMA

solid, ≥98% (HPLC)

Sinonimo/i:

4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride

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Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₉H₂₂N₄O₂S · 2HCl · xH₂O

Numero CAS:

147416-96-4

Peso molecolare:

443.39 (anhydrous basis)

NACRES:

NA.77

PubChem Substance ID:

24277875

UNSPSC Code:

12352200

MDL number:

MFCD11045947

Assay:

≥98% (HPLC)

Form:

solid

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Proprietà

Quality Segment

100

assay

≥98% (HPLC)

form

solid

color

white

solubility

H₂O: >10 mg/mL

SMILES string

O.Cl.Cl.CN1CCN(CC1)CC(=O)N2c3ccccc3NC(=O)c4csc(C)c24

InChI

1S/C19H22N4O2S.2ClH.H2O/c1-13-18-14(12-26-13)19(25)20-15-5-3-4-6-16(15)23(18)17(24)11-22-9-7-21(2)8-10-22;;;/h3-6,12H,7-11H2,1-2H3,(H,20,25);2*1H;1H2

InChI key

HZWCRPGARSMPNS-UHFFFAOYSA-N

Gene Information

human ... CHRM1(1128)

Descrizione

Application

Telenzepine dihydrochloride hydrate was used to study M₁ muscarinic receptor-mediated signaling in juvenile rat hippocampus[1] and rat urinary bladder.[2]

Biochem/physiol Actions

Telenzepine is an analog of pirenzepine and inhibits the secretion of gastric acid. It is an antagonist to M₁-receptor and targets the oxyntic gastric glands and the salivary glands.[3]

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Questo articolo	P7412	A8106	G7798
Sigma-Aldrich T122 Telenzepine dihydrochloride hydrate	Sigma-Aldrich P7412 Pirenzepine dihydrochloride	Sigma-Aldrich A8106 Altanserin	Sigma-Aldrich G7798 GYKI-53655 hydrate
assay ≥98% (HPLC)	assay ≥98% (TLC)	assay ≥98% (HPLC)	assay >99.0% (HPLC)
form solid	form powder	form solid	form powder
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
solubility H₂O: >10 mg/mL	solubility H₂O: 50 mg/mL	solubility DMSO: >5 mg/mL, H₂O: insoluble	solubility H₂O: >10 mg/mL
color white	color white to light yellow	color -	color yellow to orange
Gene Information human ... CHRM1(1128)	Gene Information human ... CHRM1(1128)	Gene Information -	Gene Information -

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Lot/Batch Number

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