SRP4908

Visfatin

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

• Sinonimo/i: Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog
• Codice UNSPSC: 12352200

Proprietà

• Origine biologica: mouse
• Ricombinante: expressed in E. coli
• Saggio: ≥95% (HPLC); ≥95% (SDS-PAGE)
• Stato: lyophilized
• PM: ~55.0 kDa
• Confezionamento: pkg of 10 μg
• Condizioni di stoccaggio: avoid repeated freeze/thaw cycles
• Impurezze: endotoxin, tested
• N° accesso NCBI: Q99KQ4
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: mouse ... Nampt(59027)

Descrizione

Descrizione generale

Visfatin is also called pre-B cell colony enhancing factor, nicotinamide phosphoribosyltransferase, pre-B-cell colony-enhancing factor 1 homolog, NAmPRTase, Nampt and PBEF. Visfatin is an adipocytokine produced by visceral fat.

Azioni biochim/fisiol

Visfatin has a role in mammalian nicotinamide adenine dinucleotide (NAD⁺) biosynthesis. Studies have shown that mice deficient in visfatin in the forebrain excitatory neurons show hyperactivity, diminished anxiety-like behaviors and impaired learning and memory. It has also been shown that visfatin stimulates glucose uptake and adenosine monophosphate-activated protein kinase (AMPK) phosphorylation in mouse C2C12 skeletal muscle cells.

Stato fisico

Lyophilized without any additives.

Ricostituzione

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in PBS to the concentration of 0.1-1 mg/mL.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable