SML3464

Gossypetin

≥98% (HPLC), MKK3 and MKK6 protein kinases inhibitor, powder

• Sinonimo/i: 2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-1-benzopyran-4-one, 8-Hydroxyquercetin, Articulatidin, Equisporol
• Formula empirica (notazione di Hill): C₁₅H₁₀O₈
• Numero CAS: 489-35-0
• Peso molecolare: 318.24
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD00017680
• Assay: ≥98% (HPLC)
• Form: powder

Proprietà

• Nome del prodotto: Gossypetin, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: , light green to yellow
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: OC1=CC(O)=C2C(C(O)=C(OC2=C1O)C3=CC=C(C(O)=C3)O)=O
• InChI: 1S/C15H10O8/c16-6-2-1-5(3-7(6)17)14-13(22)12(21)10-8(18)4-9(19)11(20)15(10)23-14/h1-4,16-20,22H
• InChI key: YRRAGUMVDQQZIY-UHFFFAOYSA-N

Descrizione

Biochem/physiol Actions

Antioxidant, antibacterial, anticancer; potent inhibitor of MKK3 and MKK6 protein kinases

Gossypetin is a hexahydroxylated flavonoid found in the flowers and the calyx of Hibiscus, which exhibits numerous pharmacological effects, including antioxidant, antibacterial and anticancer activities. It induces apoptosis and autophagic cell death in prostate cancer cells. Gossypetin is a potent inhibitor of MKK3 and MKK6 protein kinases that suppresses esophageal cancer growth.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable