SML3328

Methyl protodioscin

≥98% (HPLC)

• Sinonimo/i: (3β,​22α,​25R)​-​26-​(β-​D-​Glucopyranosyloxy)​-​22-​methoxyfurost-​5-​en-​3-​yl O-​6-​deoxy-​α-​L-​mannopyranosyl-​(1→2)​-​O-​[6-​deoxy-​α-​L-​mannopyranosyl-​(1→4)​]​-β-​D-​glucopyranoside, 22-O-Methylprotodioscin, Methylprotodioscin, NSC 698790
• Formula empirica (notazione di Hill): C₅₂H₈₆O₂₂
• Numero CAS: 54522-52-0
• Peso molecolare: 1063.23
• UNSPSC Code: 12352200
• NACRES: NA.77
• Form: powder
• Assay: ≥98% (HPLC)

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: O1[C@H]([C@@H]([C@@H]([C@H]([C@@H]1C)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O[C@@H]9O[C@H]([C@@H]([C@H]([C@H]9O)O)O)C)CO)O[C@H]3CC[C@@]4([C@@H]5[C@H]([C@H]6[C@@]([C@@H]7[C@@H](O[C@]([C@H]7C)(OC)CC[C@H](CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C)C6
• InChI: 1S/C52H86O22/c1-21(20-66-46-40(61)39(60)36(57)31(18-53)70-46)10-15-52(65-7)22(2)33-30(74-52)17-29-27-9-8-25-16-26(11-13-50(25,5)28(27)12-14-51(29,33)6)69-49-45(73-48-42(63)38(59)35(56)24(4)68-48)43(64)44(32(19-54)71-49)72-47-41(62)37(58)34(55)23(3)67-47/h8,21-24,26-49,53-64H,9-20H2,1-7H3/t21-,22+,23+,24+,26+,27-,28+,29+,30+,31-,32-,33+,34+,35+,36-,37-,38-,39+,40-,41-,42-,43+,44-,45-,46-,47+,48+,49-,50+,51+,52-/m1/s1
• InChI key: HSSJYSJXBOCKQM-GVTGEURHSA-N

Descrizione

Biochem/physiol Actions

Methyl protodioscin is a saponin isolated from medical plant Dioscoreaceae that exhibit anticancer properties. It appears that Methyl protodioscin inhibits proliferation and promoted apoptosis of pancreatic cancer through suppression of glycolysis. Methyl protodioscin protects rat brain from I/R injury through down-regulation Mul1 (Mitochondrial E3 ubiquitin ligase 1) and elevation of SOD2 (superoxide dismutase 2) protein levels.

Saponin isolated from medical plant Dioscoreaceae that exhibit anticancer properties and protects rat brain from I/R injury

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable