SML2999

KL201

≥97% (HPLC)

• Sinonimo/i: 2-Bromo-N-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)-benzamide
• Formula empirica (notazione di Hill): C₁₇H₁₄BrN₃OS
• Numero CAS: 302939-48-6
• Peso molecolare: 388.28
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥97% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 100
• assay: ≥97% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(C1=CC=CC=C1Br)NC2=NC=NC3=C2C4=C(CCCC4)S3
• InChI: 1S/C17H14BrN3OS/c18-12-7-3-1-5-10(12)16(22)21-15-14-11-6-2-4-8-13(11)23-17(14)20-9-19-15/h1,3,5,7,9H,2,4,6,8H2,(H,19,20,21,22)
• InChI key: KFSLRFWIPVMBNT-UHFFFAOYSA-N

Descrizione

Biochem/physiol Actions

KL201 is a circadian clock modulator that lengthens a circadian period in cells and tissues. KL201 selectively regulate cryptochrome 1 (Cry1). It binds to FAD-binding pocket of CRY1 preventing interaction with FBXL3 and ubiquitin-dependent degradation.

circadian clock modulator that lengthens a circadian period; stabilizes cryptochrome 1 (Cry1)

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable