SML1489
FICZ
≥95% (HPLC), lyophilized powder, AhR agonist
Sinonimo/i:
5,11-Dihydro-indolo[3,2-b]carbazole-6-carboxaldehyde, 6-Formylindolo[3,2-b]carbazole
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About This Item
Formula empirica (notazione di Hill):
C19H12N2O
Numero CAS:
Peso molecolare:
284.31
Codice UNSPSC:
12352200
NACRES:
NA.77
Prodotti consigliati
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product name
FICZ, ≥95% (HPLC)
Livello qualitativo
Saggio
≥95% (HPLC)
Forma fisica
lyophilized powder
Colore
yellow
Solubilità
DMSO: 0.5 mg/mL, clear (warmed)
Temperatura di conservazione
−20°C
Azioni biochim/fisiol
FICZ (6-formylindolo(3,2b)carbazole) being a photooxidation product of tryptophan, might serve as a chemical messenger of light.
FICZ is a potent high affinity ligand of the aryl hydrocarbon receptor (AhR), which is a ligand-activated transcription factor that activates the expression of aromatic hydrocarbon metabolizing enzyme genes such as the CYP1A1 gene and has also been shown to have multiple additional roles in cell-cycle regulation, development and maturation of many tissues, control of inflammation, and immune response. FICZ is a photoproduct of tryptophan and is believed to be an endogenous AhR ligand. It is extremely potent, with a Kd value of 0.07 nM.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Oral
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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