SML0690

L-161,982

≥98% (HPLC)

• Sinonimo/i: N-[[4′-[[3-Butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1"-biphenyl]-2-yl]sulfonyl]-3-methyl-2-thiophenecarboxamide
• Formula empirica (notazione di Hill): C₃₂H₂₉F₃N₄O₄S₂
• Numero CAS: 147776-06-5
• Peso molecolare: 654.72
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)c1c(cccc1)[n]2nc([n]([c]2=O)Cc3ccc(cc3)c4c(cccc4)[S](=O)(=O)NC(=O)c5[s]ccc5C)CCCC
• InChI: 1S/C32H29F3N4O4S2/c1-3-4-13-28-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(28)20-22-14-16-23(17-15-22)24-9-5-8-12-27(24)45(42,43)37-30(40)29-21(2)18-19-44-29/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40)
• InChI key: MMDNKTXNUZFVKD-UHFFFAOYSA-N

Descrizione

Biochem/physiol Actions

L-161,982 is a potent EP4 receptor antagonist that is selective over all other members of the prostanoid receptor family (Ki values are 0.024, 0.71, 1.90, 5.10, 5.63, 6.74, 19 and 23 μM for human EP4, TP, EP3, DP, FP, IP, EP1 and EP2 receptors respectively.

L-161,982 is a potent EP4 receptor antagonist.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable