SML0338

Lornoxicam

≥98% (HPLC)

• Sinonimo/i: 6-Chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide, Chlortenoxicam, Ro 13-9297, TS 110
• Formula empirica (notazione di Hill): C₁₃H₁₀ClN₃O₄S₂
• Numero CAS: 70374-39-9
• Peso molecolare: 371.82
• NACRES: NA.77
• PubChem Substance ID: 329825343
• UNSPSC Code: 12352200
• MDL number: MFCD00866163
• Assay: ≥98% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: faintly yellow to dark yellow
• solubility: DMSO: >5 mg/mL (warmed)
• storage temp.: −20°C
• SMILES string: CN1C(C(=O)Nc2ccccn2)=C(O)c3sc(Cl)cc3S1(=O)=O
• InChI: 1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
• InChI key: WLHQHAUOOXYABV-UHFFFAOYSA-N

Descrizione

General description

Lornoxicam belongs to the oxicam class. It has anti-inflammatory and antipyretic properties. Lornoxicam prevents the synthesis of prostaglandin (PG) by inhibiting cyclo-oxygenase. It is used to relieve various types of symptoms associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute sciatica and low back pain.

Application

Lornoxicam has been used as a drug in melanin binding study with cassette dosing and rapid equilibrium dialysis inserts.

Biochem/physiol Actions

Lornoxicam is an oxicam-class NSAID with strong analgesic properties.

Lornoxicam is an oxicam-class NSAID; cyclooxygenase inhibitor.

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Parola di avvertenza: Danger
• Codici di pericolo: H300
• Avvertenze di sicurezza: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 2 Oral
• Classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable