SMB00584

Gastrodin

from Gastrodia alata, ≥98%

• Sinonimo/i: (2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-(4-hydroxymethyl-phenoxy)-tetrahydro-pyran-3,4,5-triol, 4-β-D-glucopyranosyloxybenzyl alcohol, 4-Hydroxybenzyl alcohol 4-O-β-D-glucoside
• Formula empirica (notazione di Hill): C₁₃H₁₈O₇
• Numero CAS: 62499-27-8
• Peso molecolare: 286.28
• Numero MDL: MFCD00272169
• Codice UNSPSC: 41116107
• ID PubChem: 329825072
• NACRES: NA.25

Proprietà

• Saggio: ≥98%
• Stato: powder
• applicazioni: metabolomics; vitamins, nutraceuticals, and natural products
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O[C@@H]1[C@@H](CO)O[C@@H](OC2=CC=C(CO)C=C2)[C@H](O)[C@H]1O
• InChI: 1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1; PUQSUZTXKPLAPR-UJPOAAIJSA-N

Descrizione

Descrizione generale

Gastrodin, a phenolic glucoside, is the main active ingredient of the Traditional Chinese medicinal compound Tianma. Gastrodin can penetrate through the blood-brain barrier and has been suggested to have neuroprotective effects against hypoxia. It is also known to reduce the immunoreactivity of γ-aminobutyric acid shunt enzymes in hippocampal tissues.[1]

Azioni biochim/fisiol

Gastrodin is a key bioactive component. The study shows that its clinical application is widely distributed in the treatment of neurasthenia, dizziness, epilepsy, migraine, headache and dementia. Its pharmacological impacts has also been reported in cardiovascular diseases and neointima formation.[2]

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P264 - P270 - P301 + P312 - P501
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable