SAB4702104

Monoclonal Anti-CD271, purified produced in mouse

• Sinonimo/i: NGFR, TNFRSF16, p75NGFR, p75NTR
• Codice UNSPSC: 12352203

Proprietà

• Coniugato: unconjugated
• Livello qualitativo: 100
• Tipo di anticorpo: primary antibodies
• Clone: NGFR5, monoclonal
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human, ( Non-human primates), ( Rabbit), ( Cat)
• Concentrazione: 1 mg/ml
• tecniche: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotipo: IgG1
• N° accesso UniProt: P08138
• Temperatura di conservazione: 2-8°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... NGFR(4804)

Descrizione

Descrizione generale

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

Specificità

The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

Immunogeno

Purified CD271 protein isolated from human melanoma cell line A875

Stato fisico

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota sulla preparazione

Purified by protein-A affinity chromatography.

Stoccaggio e stabilità

Store at 2-8°C. Do not freeze.

Altre note

The antibody solution should be gently mixed before use.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable