SAB4702019

Monoclonal Anti-CD82 purified low endotoxin produced in mouse

• Sinonimo/i: 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
• Codice UNSPSC: 12352203

Proprietà

• Coniugato: unconjugated
• Livello qualitativo: 100
• Tipo di anticorpo: primary antibodies
• Clone: C33, monoclonal
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• Concentrazione: 1 mg/ml
• tecniche: FUNC: suitable; flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotipo: IgG2a
• N° accesso UniProt: P27701
• Temperatura di conservazione: 2-8°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... CD82(3732)

Descrizione

Descrizione generale

CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.

Specificità

The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.

Immunogeno

C91/PL (human HTLV-1+ T cell line)

Stato fisico

Phosphate buffered saline (PBS), pH 7.4

Nota sulla preparazione

Purified by protein-A affinity chromatography.

Stoccaggio e stabilità

Store at 2-8°C. Do not freeze.

Altre note

The antibody solution should be gently mixed before use.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1