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SAB4503695

Sigma-Aldrich

Anti-GASP1 antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

G-protein coupled receptor-associated sorting protein 1, GASP, GASP-1, GPRASP1, KIAA0443

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

PM

antigen 156 kDa

Reattività contro le specie

human

Concentrazione

~1 mg/mL

tecniche

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

N° accesso NCBI

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... GASP1(9737)

Descrizione generale

Anti-GASP1 Antibody detects endogenous levels of total GASP1 protein.
G-protein coupled receptor-associated sorting protein 1 (GASP-1) is expressed at high level in the olfactory bulb, hippocampus, hypothalamus and some thalamic and cortical regions. It is located on human chromosome Xq22. It is also termed as WFIKKNRP or WFIKKN2. GASP-1 has a whey acidic protein domain, a follistatin/Kazal domain, an Ig domain, two tandem Kunitz domains and a netrin domain.

Immunogeno

The antiserum was produced against synthesized peptide derived from human GASP1.

Immunogen Range: 741-790

Azioni biochim/fisiol

G-protein coupled receptor-associated sorting protein 1 (GASP-1) acts as a ubiquitous tumor marker. It plays an important role in the post endocytic sorting process. It is also expected to play a major role in recycling and degradation of several G-protein-coupled receptors (GPCRs).

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2
Lee YS and Lee SJ
Proceedings of the National Academy of Sciences of the USA (2013)
G-protein coupled receptor-associated sorting protein 1 (GASP-1), a ubiquitous tumor marker
Zheng X, et al.
Experiments in Microbial Genetics, 93(1), 111-115 (2012)
Impaired striatum-dependent behavior in GASP-1-knock-out mice
Mathis C, et al.
Genes, Brain, and Behavior, 10(3), 299-308 (2011)
A novel Xq22.1 deletion in a male with multiple congenital abnormalities and respiratory failure
Cao Y and Aypar U
European Journal of Medical Genetics, 59(5), 274-277 (2016)
Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1
Martini L, et al.
Faseb Journal, 21(3), 802-811 (2007)

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