SAB4501633

Anti-KCNJ5 antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: G protein-activated inward rectifier potassium channel 4, GIRK4, Inward rectifier K(+) channel Kir3.4, Potassium channel, inwardly rectifying subfamily J member 5
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 47 kDa
• Reattività contro le specie: human
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:5000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• N° accesso NCBI: P48544
• N° accesso UniProt: P48544
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... KCNJ5(3762)

Descrizione

Descrizione generale

Anti-KCNJ5 Antibody detects endogenous levels of total KCNJ5 protein.
KCNJ5 (potassium voltage-gated channel subfamily J member 5) is an inwardly rectifying potassium channel, which is also termed as GIRK4 (G protein-coupled inward rectifier K⁺ channel 4). It is expressed in the cerebral cortex. This gene is mapped to human chromosome 11q24.

Immunogeno

The antiserum was produced against synthesized peptide derived from human KCNJ5.

Immunogen Range: 370-419

Azioni biochim/fisiol

KCNJ5 (potassium voltage-gated channel subfamily J member 5) is associated with aldosteronism, a major cause of secondary hypertension. Mutated KCNJ5 gene affects the polarization of plasma membrane and permit sodium and calcium inflow into the cells.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable