SAB4300425

Anti-GRIN2B (Ab-1474) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-MGC142178 antibody produced in rabbit, Anti-MGC142180 antibody produced in rabbit, Anti-NMDAR2B antibody produced in rabbit, Anti-NR2B antibody produced in rabbit, Anti-glutamate receptor, ionotropic, N-methyl D-aspartate 2B antibody produced in rabbit
• Numero MDL: MFCD00243314
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Stato: buffered aqueous solution
• PM: ~190 kDa
• Reattività contro le specie: human, rat, mouse
• Concentrazione: 1 mg/mL
• tecniche: indirect immunofluorescence: 1:100-1:200
• Isotipo: IgG
• Sequenza immunogenica: (H-V-Y-E-K)
• N° accesso NCBI: NP_000825.2
• N° accesso UniProt: Q13224
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... GRIN2B(2904)

Descrizione

Descrizione generale

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) codes for N-methyl d-aspartate receptor subtype 2B (GluN2B). It belongs to the N-methyl-D-aspartate receptor (NMDAR) gene family. It is located on human chromosome 12p13.1.

Immunogeno

Peptide sequence around aa. 1472-1476 (H-V-Y-E-K), according to the protein GRIN2B.

Azioni biochim/fisiol

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) plays an important role in the growth of neurons and is highly essential for the learning and memory. GRIN2B mutation is associated with neuropsychiatric and developmental disorders like schizophrenia, Parkinson′s disease and bipolar disorder.

Caratteristiche e vantaggi

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Descrizione del bersaglio

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable