SAB4300113

Anti-phospho-FOXO4 (pSer¹⁹⁷) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-AFX antibody produced in rabbit, Anti-AFX1 antibody produced in rabbit, Anti-MGC120490 antibody produced in rabbit, Anti-MLLT7 antibody produced in rabbit, Anti-forkhead box O4 antibody produced in rabbit
• Numero MDL: MFCD03791410
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: ~65 kDa
• Reattività contro le specie: human, rat, mouse
• Concentrazione: 1 mg/mL
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotipo: IgG
• Sequenza immunogenica: (A-A-SP-M-D)
• N° accesso NCBI: NP_001164402.1
• N° accesso UniProt: P98177
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pSer197)
• Informazioni sul gene: human ... FOXO4(4303)

Descrizione

Immunogeno

Peptide sequence around phosphorylation site of serine 197 (A-A-S(p)-M-D), according to the protein FOXO4.

Caratteristiche e vantaggi

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Descrizione del bersaglio

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable