SAB4300045

Anti-phospho-NBN (pSer³⁴³) antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-AT-V1 antibody produced in rabbit, Anti-AT-V2 antibody produced in rabbit, Anti-ATV antibody produced in rabbit, Anti-FLJ10155 antibody produced in rabbit, Anti-nibrin antibody produced in rabbit
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: ~95 kDa
• Reattività contro le specie: human
• Concentrazione: 1 mg/mL
• tecniche: western blot: 1:500-1:1000
• Isotipo: IgG
• Sequenza immunogenica: (S-L-SP-Q-G)
• N° accesso NCBI: NP_002476.2
• N° accesso UniProt: O60934
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pSer343)
• Informazioni sul gene: human ... NBN(4683)

Descrizione

Immunogeno

Peptide sequence around phosphorylation site of serine 343 (S-L-S(p)-Q-G), according to the protein NBN.

Caratteristiche e vantaggi

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Descrizione del bersaglio

Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable