SAB3500457

Anti-TEM4 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinonimo/i: Anti-ARHGEF17, Anti-P164RHOGEF, Anti-Rho guanine nucleotide exchange factor 17, Anti-Tumor endothelial marker 4
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: predicted mol wt 220 kDa
• Reattività contro le specie: human
• tecniche: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• N° accesso NCBI: Q96PE2
• N° accesso UniProt: Q96PE2
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ARHGEF17(9828)

Descrizione

Descrizione generale

Rho guanine nucleotide exchange factor 17 (ARHGEF17), also known as tumor endothelial marker 4 (TEM4) and p164-RhoGEF (Rho-specific guanine-nucleotide exchange factor), encodes a guanine nucleotide exchange factor (GEF) for RhoA GTPases. The encoded protein consists of 1510 amino acids and contains a RhoGEF-specific Dbl homology (DH) domain. It does not contain the typical pleckstrin homology domain. TEM4 is predominantly expressed in the heart. Overexpression of this protein inhibits the transcription of M3 muscarinic receptor-induced genes. TEM4 modulates endothelial cell migration.

Immunogeno

TEM4 antibody was raised against a 18 amino acid peptide near the center of human TEM4.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500457.

Stato fisico

Supplied in PBS with 0.02% sodium azide.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable