SAB3500315

Anti-TRIAD3A antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: IgG fraction of antiserum
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: predicted mol wt 95 kDa
• Reattività contro le specie: mouse, human
• tecniche: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• N° accesso NCBI: AAP47174
• N° accesso UniProt: Q9NWF9
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... RNF216(54476)

Descrizione

Descrizione generale

Ring finger protein 216 (RNF216) is an E3 ubiquitin ligase. The gene encoding this protein is localized on human chromosome 7p22.3.

Immunogeno

TRIAD3A antibody was raised against a peptide corresponding to 15 amino acids near the amino-terminus of mouse TRIAD3A.

Azioni biochim/fisiol

Ring finger protein 216 (RNF216) associates with toll-like receptors and aids in their degradation. It also aids in the degradation of receptor interacting protein-1 (RIP-1) kinase and negatively modulates tumor necrosis α receptor signaling. The protein acts as an inhibitor of autophagy in macrophages. Mutations in the RNF216 gene have been associated with Gordon Holmes syndrome.

Caratteristiche e vantaggi

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Linkage

The action of this antibody can be blocked using blocking peptide SBP3500315.

Stato fisico

Supplied in PBS with 0.02% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable