S5068

Salmeterol xinafoate

≥98% (HPLC), solid

• Sinonimo/i: (±) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol xinafoate, GR 33343X xinafoate
• Formula empirica (notazione di Hill): C₂₅H₃₇NO₄ · C₁₁H₈O₃
• Numero CAS: 94749-08-3
• Peso molecolare: 603.75
• Numero MDL: MFCD00897708
• Codice UNSPSC: 12352200
• ID PubChem: 24278713
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Forma fisica: solid
• Colore: white
• Solubilità: H₂O: slightly soluble; ethanol: slightly soluble; methanol: freely soluble
• Ideatore: GlaxoSmithKline
• Stringa SMILE: OC(=O)c1ccc2ccccc2c1O.OCc3cc(ccc3O)C(O)CNCCCCCCOCCCCc4ccccc4
• InChI: 1S/C25H37NO4.C11H8O3/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21;12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2;1-6,12H,(H,13,14); XTZNCVSCVHTPAI-UHFFFAOYSA-N
• Informazioni sul gene: human ... ADRB2(154)

Descrizione

Applicazioni

Salmeterol xinafoate was used as conjugate with human serum albumin to study the immune responses in rabbits.⁷

Azioni biochim/fisiol

Salmeterol xinafoate is a β2 adrenoceptor agonist with longer lasting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles, stabilizes mast cells and regulates the release of histamine. Salmetrol is particularly effective in treatment of mild asthma, chronic obstructive pulmonary disorder.^5,6

β₂-adrenoceptor agonist.

Caratteristiche e vantaggi

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)