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RAB0711

Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit

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A voi/SKUDisponibilitàPrezzo
96 wells
Per conoscere la disponibilità, visualizza il carrello
CHF 822.00

Informazioni su questo articolo

NACRES:
NA.84
UNSPSC Code:
41116158
Gene information:
human ... CSF1R(1436)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice

CHF 822.00


Per conoscere la disponibilità, visualizza il carrello

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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CSF1R(1436)

General description

CSF1R (colony stimulating factor 1 receptor) is a member of the platelet-derived growth factor (PDGF) family of proteins and is a type III RTK (receptor tyrosine kinase). CSF1R is composed of five immunoglobulin (Ig)-like domains, a transmembrane region, a juxtamembrane domain and kinase insert domain (KID) intersecting the kinase domain.
The antibody pair provided in this kit recognizes human Macrophage Colony-stimulating Factor 1 Receptor.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

CSF1R (colony stimulating factor 1 receptor) acts as a receptor for CSF1 and regulates monocyte and macrophage functioning. The protein and its ligand are linked to poor prognosis in patients with solid tumors and in patients with female reproductive cancers. In breast cancers, with decreased claudin levels, this protein regulates the switch between proliferative and invasive state of the tumor, acting downstream of TGFβ (tumor growth factor β). Haploinsufficiency in this receptor might lead to aberration of microglial function, which might be a contributor to the pathogenesis of hereditary diffuse leukoencephalopathy with spheroids (HDLS).

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Questo articolo
RAB0098RAB0680RAB0731
description

-

description

for serum, plasma, cell culture supernatant, urine

description

-

description

-

Gene Information

human ... CSF1R(1436)

Gene Information

human ... CSF1(1435)

Gene Information

human ... IGF2R(3482)

Gene Information

human ... KIT(3815)

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

assay range

inter-assay cv: <10%
intra-assay cv: <12%

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.78-2000 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.27 ng/mL
standard curve range: 0.274-200 ng/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/mL
standard curve range: 40.96-10000 pg/mL

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
SDS & Determinazione del prezzo

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    SDS

  • ELISA Stop Solution (Item I)
    SDS

  • 20X Wash Buffer (Item B)
    SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Classe di stoccaggio

10 - Combustible liquids



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