RAB0629
Human GDF2 / Growth/Differentiation Factor 2 ELISA Kit
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96 WELLS
CHF 594.00
CHF 594.00
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Cambia visualizzazione
96 WELLS
CHF 594.00
About This Item
Codice UNSPSC:
41116158
NACRES:
NA.32
CHF 594.00
Check Cart for Availability
Reattività contro le specie
human
Confezionamento
kit of 96 wells (12 strips x 8 wells)
tecniche
ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 32 pg/mL
standard curve range: 32.77-8000 pg/mL
Metodo di rivelazione
colorimetric
Condizioni di spedizione
wet ice
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... GDF2(2658)
Categorie correlate
Descrizione generale
The growth differentiation factor 2 (GDF2) gene encodes for bone morphogenic protein 9 (BMP9).[1] GDF2, also known as BMP9, belongs to the BMP family.[2] The GDF2 gene is mapped on the human chromosome at 10q11.22.[3] GDF2/BMP9 protein regulates angiogenesis, modulating tumorigenesis, inhibiting hepatic glucose production, and maintaining basal forebrain cholinergic neurons.[2] It is implicated in the pathogenesis of pulmonary arterial hypertension.[2] Mutations in the GDF2 gene are associated with hereditary hemorrhagic telangiectasia (HHT), an autosomal dominant vascular disorder.[1] The antibody pair provided in this kit recognizes human growth/differentiation factor 2.
Applicazioni
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Met. Corr. 1
Codice della classe di stoccaggio
8A - Combustible corrosive hazardous materials
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Z Yang et al.
Science advances, 6(48) (2020-11-29)
Obesity drives the development of nonalcoholic fatty liver disease (NAFLD) characterized by hepatic steatosis. Several bone morphogenetic proteins (BMPs) except BMP9 were reported related to metabolic syndrome. This study demonstrates that liver cytokine BMP9 is decreased in the liver and
Wei Liu et al.
Genes & diseases, 7(2), 235-244 (2020-03-28)
Bone morphogenetic protein 9 (BMP9) (or GDF2) was originally identified from fetal mouse liver cDNA libraries. Emerging evidence indicates BMP9 exerts diverse and pleiotropic functions during postnatal development and in maintaining tissue homeostasis. However, the expression landscape of BMP9 signaling
Felicia Hernandez et al.
Human genome variation, 2, 15040-15040 (2015-01-01)
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder caused by mutations in ENG, ACVRL1 and SMAD4, which function in regulating the transforming growth factor beta and bone morphogenetic protein signaling pathways. Symptoms of HHT can be present in
Yongyun Li et al.
Journal of molecular and cellular cardiology, 147, 92-107 (2020-07-31)
Venous malformation (VM) is a type of vascular morphogenic defect in humans with an incidence of 1%. Although gene mutation is considered as the most common cause of VM, the pathogenesis of those without gene mutation remains to be elucidated.
Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.
Saus, et al.
Journal of Psychiatric Research, 44, 971-978 (2018)
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