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RAB0539

Sigma-Aldrich

Human AHSG / Alpha-2-HS-glycoprotein ELISA Kit

for serum, plasma and cell culture supernatants

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96 WELLS
CHF 502.00

CHF 502.00


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96 WELLS
CHF 502.00

About This Item

Codice UNSPSC:
41116158
NACRES:
NA.32

CHF 502.00


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Reattività contro le specie

human

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable

input

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.2 ng/mL

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... AHSG(197)

Descrizione generale

This ELISA antibody pair detects human Alpha-2-HS-glycoprotein.

Applicazioni

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Azioni biochim/fisiol

α 2-HS glycoprotein (AHSG), also referred to as fetuin-A, is a major serum protein component that exerts various calcium-dependent physiological activities and can mediate growth signaling in certain tumor cells.[1] It can also act as a natural antagonist against specific TGF-β (transforming growth factor β) and BMP (bone morphogenetic protein) signaling proteins. High levels of fetuin-A in the serum is associated with mild osteogenesis imperfecta. On the other hand, reduced levels are seen in Paget′s disease.[2] It is predicted as a potential biomarker for the early diagnosis of hypopharyngeal squamous cell carcinoma.[3]

Altre note

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
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  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pittogrammi

Corrosion

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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alpha 2-HS glycoprotein/fetuin, a transforming growth factor-beta/bone morphogenetic protein antagonist, regulates postnatal bone growth and remodeling.
Szweras M, et al.
The Journal of Biological Chemistry, 277(22), 19991-19997 (2002)
Nina Ferrari et al.
BMC sports science, medicine & rehabilitation, 12, 55-55 (2020-09-19)
The prevalence of obesity in childhood is increasing worldwide and may be affected by genetic factors and the lifestyle (exercise, nutrition behavior) of expectant parents. Lifestyle factors affect adipokines, namely leptin, resistin, and adiponectin as well as cytokines such as
Reza Afrisham et al.
Diabetology & metabolic syndrome, 12, 32-32 (2020-04-24)
It is generally accepted that obesity can lead to metabolic disorders such as NAFLD and insulin resistance. However, the underlying mechanism has been poorly understood. Moreover, there is evidence to support the possible role of exosomes in the metabolic homeostasis
Chia-Ter Chao et al.
Journal of the American Heart Association, 8(2), e010805-e010805 (2019-01-17)
Background Micro RNA -125b (miR-125b) has been shown to regulate vascular calcification ( VC ), and serum miR-125b levels are a potential biomarker for estimating the risk of uremic VC status. However, it is unknown whether clinical features, including chronic
Claas Jasper Steffen et al.
Archives of orthopaedic and trauma surgery, 140(10), 1359-1366 (2019-12-21)
In the elderly, osteoporotic fractures of the femur are associated with high morbidity and mortality. At the time of hospitalization and during pre-operative care identification of patients at risk for poor outcome despite an otherwise good clinical condition is challenging.

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