The epitope recognized by PLA0005 maps to a region between residue 50 and 100 of human Heterochromatin Protein p25 beta (Chromobox Homolog 1) using the numbering given in entry NP_006798.1 (GeneID 10951).
Stato fisico
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide
Altre note
Heterochromatin protein 1 beta (HP1-beta) is a heterochromatin-associated protein that bears an evolutionarily conserved chromodomain (CD) and chromoshadow domain (CSD) that mediates chromatin and protein-protein interactions, respectively. HP1 associates with pericentromeric DNA and plays a role in gene silencing and heterochromatin formation.
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