P9180
Procaterol hydrochloride
Sinonimo/i:
erythro-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-2(1H)-quinolinone
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About This Item
Formula empirica (notazione di Hill):
C16H22N2O3 · HCl
Numero CAS:
Peso molecolare:
326.82
Numero CE:
Numero MDL:
Codice UNSPSC:
12352202
ID PubChem:
NACRES:
NA.77
Prodotti consigliati
Stato
powder
Livello qualitativo
Temperatura di conservazione
2-8°C
Stringa SMILE
Cl.CC[C@H](NC(C)C)[C@H](O)c1ccc(O)c2NC(=O)C=Cc12
InChI
1S/C16H22N2O3.ClH/c1-4-12(17-9(2)3)16(21)11-5-7-13(19)15-10(11)6-8-14(20)18-15;/h5-9,12,16-17,19,21H,4H2,1-3H3,(H,18,20);1H/t12-,16+;/m0./s1
AEQDBKHAAWUCMT-CVHDTDHSSA-N
Descrizione generale
Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.
Azioni biochim/fisiol
β2-adrenoceptor agonist; bronchodilator.
Caratteristiche e vantaggi
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Confezionamento
Bottomless glass bottle. Contents are inside inserted fused cone.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Yukiko Hiraguchi et al.
International archives of allergy and immunology, 155 Suppl 1, 85-89 (2011-06-10)
Viral respiratory tract infections play an important role in the inception and exacerbation of asthma. Eosinophils, major effector cells in asthma, often accumulate in the airways during viral infections and are possibly activated by respiratory RNA viruses through Toll-like receptor
Ethanolamines: Advances in Research and Application (2012)
F Preitner et al.
British journal of pharmacology, 124(8), 1684-1688 (1998-10-02)
The beta3-adrenoceptor plays an important role in the adrenergic response of brown and white adipose tissues (BAT and WAT). In this study, in vitro metabolic responses to beta-adrenoceptor stimulation were compared in adipose tissues of beta3-adrenoceptor knockout and wild type
Mutsuo Yamaya et al.
European journal of pharmacology, 650(1), 431-444 (2010-10-14)
β(2) agonists reduce the frequency of exacerbations in patients with bronchial asthma and chronic obstructive pulmonary disease caused by respiratory virus infection. β(2) agonists reduce the production of pro-inflammatory cytokines. However, the inhibitory effects of β(2) agonists on the infection
Masahiro Satake et al.
Arzneimittel-Forschung, 61(1), 8-13 (2011-03-02)
The purpose of this study was to evaluate the inhibitory effect of procaterol (procaterol hydrochloride, CAS 62929-91-3) on exercise dynamic lung hyperinflation during the 6-min walk test (6MWT) in stable chronic obstructive disease (COPD) patients. Fourteen patients with stable COPD
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