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P9178

Sigma-Aldrich

Prochlorperazine dimaleate salt

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About This Item

Formula empirica (notazione di Hill):
C20H24ClN3S · 2C4H4O4
Numero CAS:
84-02-6
Peso molecolare:
606.09
Numero CE:
201-511-3
Numero MDL:
MFCD00069330
Codice UNSPSC:
41116107
ID PubChem:
57654570
NACRES:
NA.77

Forma fisica

powder

Solubilità

H2O: slightly soluble 0.3 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL
methanol: soluble

Ideatore

GlaxoSmithKline

Stringa SMILE

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1

InChI

1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
DSKIOWHQLUWFLG-SPIKMXEPSA-N

Informazioni sul gene

human ... DRD2(1813)

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Azioni biochim/fisiol

Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects. Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist; antispasmodic

Caratteristiche e vantaggi

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H336,H361d,H362

Classi di pericolo

Acute Tox. 4 Oral - Lact. - Repr. 2 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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