P9178

Prochlorperazine dimaleate salt

• Formula empirica (notazione di Hill): C₂₀H₂₄ClN₃S · 2C₄H₄O₄
• Numero CAS: 84-02-6
• Peso molecolare: 606.09
• NACRES: NA.77
• PubChem Substance ID: 57654570
• UNSPSC Code: 41116107
• EC Number: 201-511-3
• MDL number: MFCD00069330
• Form: powder

Proprietà

• form: powder
• Quality Segment: 200
• solubility: H₂O: slightly soluble 0.3 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL, methanol: soluble
• originator: GlaxoSmithKline
• SMILES string: OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1
• InChI: 1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
• InChI key: DSKIOWHQLUWFLG-SPIKMXEPSA-N
• Gene Information: human ... DRD2(1813)

Descrizione

Biochem/physiol Actions

Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects. Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.

Phenothiazine antipsychotic; D₂ dopamine receptor antagonist; antispasmodic

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Parola di avvertenza: Warning
• Codici di pericolo: H302,H336,H361d,H362
• Avvertenze di sicurezza: P202 - P260 - P263 - P264 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Lact. - Repr. 2 - STOT SE 3
• Organi bersaglio: Central nervous system
• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 3
• DPI (dispositivi di protezione individuale): dust mask type N95 (US), Eyeshields, Gloves