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P5556

Sigma-Aldrich

Poloxamer 188 solution

10%, sterile-filtered, BioReagent, suitable for insect cell culture

Sinonimo/i:

Nonionic copolymer surfactant

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About This Item

Numero CAS:
9003-11-6
Numero MDL:
MFCD00082049
Codice UNSPSC:
12161902
ID PubChem:
24898666
NACRES:
NA.75

Descrizione

non-ionic

Sterilità

sterile-filtered

Nome Commerciale

BioReagent

PM

average mol wt 8350

Concentrazione

10%

tecniche

cell culture | insect: suitable

Impurezze

endotoxin, tested

CMC

0.04 mM

Temp. transizione

cloud point ≥100

HLB

29

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
RVGRUAULSDPKGF-UHFFFAOYSA-N

Categorie correlate

Descrizione generale

Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropylene flanked at ends by hydrophilic polyoxyethylene.

Applicazioni

A nonionic copolymer surfactant

Azioni biochim/fisiol

Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence. P-188 exhibits low toxicity and may be used in oral drug delivery.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificati d'analisi (COA)

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