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P5556

Poloxamer 188 solution

10%, sterile-filtered, BioReagent, suitable for insect cell culture

Sinonimo/i:

Nonionic copolymer surfactant

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Informazioni su questo articolo

Numero CAS:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.75
MDL number:
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description

non-ionic

Quality Segment

sterility

sterile-filtered

product line

BioReagent

mol wt

average mol wt 8350

concentration

10%

technique(s)

cell culture | insect: suitable

impurities

endotoxin, tested

transition temp

cloud point ≥100

HLB

29

SMILES string

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

General description

Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropylene flanked at ends by hydrophilic polyoxyethylene.[1]

Application

A nonionic copolymer surfactant

Biochem/physiol Actions

Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence.[1][2] P-188 exhibits low toxicity and may be used in oral drug delivery.

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Questo articolo
K48941.3711216758
Kolliphor P 188 solid

Sigma-Aldrich

K4894

Kolliphor P 188

Poloxamer 188 EMPROVE® EXPERT, (stabilized with 70ppm BHT), Ph. Eur., ChP, JPE, NF

SAFC

1.37112

Poloxamer 188

technique(s)

cell culture | insect: suitable

technique(s)

-

technique(s)

API processing | nano-milling: suitable

technique(s)

-

Quality Level

400

Quality Level

300

Quality Level

500

Quality Level

100

HLB

29

HLB

-

HLB

-

HLB

-

impurities

endotoxin, tested

impurities

-

impurities

-

impurities

≤1.0% water

product line

BioReagent

product line

-

product line

EMPROVE® EXPERT

product line

-

mol wt

average mol wt 8350

mol wt

8.400 g/mol

mol wt

-

mol wt

-


Classe di stoccaggio

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Questions

1–3 of 3 Questions  
  1. what is the storage temperature for this product

    1 answer
    1. This product may be stored in room temperature.

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  2. What is this compound dissolved in ? I can not see any information about that.

    1 answer
    1. This product is a 10% solution of Poloxamer 188 in water.

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  3. How does the pH of the Poloxamer 188 solution fluctuate throughout a 24-month period?

    1 answer
    1. The pH of a solution containing Poloxamer 188 may change over time due to factors such as hydrolysis or oxidation. The pH stability of Poloxamer 188 solutions has not been conducted. However, end users are encouraged to periodically monitor the solutions to ensure their stability and efficacy.

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