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P0100

Sigma-Aldrich

Psilocybin

≥98% (HPLC), solid

Sinonimo/i:

3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl phosphate

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About This Item

Formula empirica (notazione di Hill):
C12H17N2O4P
Numero CAS:
520-52-5
Peso molecolare:
284.25
Numero CE:
208-294-4
Numero MDL:
MFCD01310431
Codice UNSPSC:
12352200
NACRES:
NA.77

Saggio

≥98% (HPLC)

Stato

solid

Controllo stupefacenti

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

Solubilità

H2O: >20 mg/mL

Temperatura di conservazione

−20°C

Stringa SMILE

CN(C)CCc1c[nH]c2cccc(OP(O)(O)=O)c12

Azioni biochim/fisiol

Psilocybin is a hallucinogenic serotonin 1A and 2A agonist and psychotomimetic.
Psilocybin is a hallucinogenic serotonin 1A and 2A agonist and psychotomimetic. It is the minor hallucinogenic component of Teonanácatl, the sacred mushroom of Mexico. Psilocybin produces muscle relaxation, dilation of pupils, vivid visual and auditory distortions, and emotional disturbances.

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H315,H319,H370

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 1

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
127K4703

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Matthew W Johnson et al.
Drug and alcohol dependence, 123(1-3), 132-140 (2011-12-02)
Psilocybin is a well-characterized classic hallucinogen (psychedelic) with a long history of religious use by indigenous cultures, and nonmedical use in modern societies. Although psilocybin is structurally related to migraine medications, and case studies suggest that psilocybin may be efficacious
Michael Kometer et al.
Biological psychiatry, 72(11), 898-906 (2012-05-15)
Serotonin (5-HT) 1A and 2A receptors have been associated with dysfunctional emotional processing biases in mood disorders. These receptors further predominantly mediate the subjective and behavioral effects of psilocybin and might be important for its recently suggested antidepressive effects. However
Robin L Carhart-Harris et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(6), 2138-2143 (2012-02-07)
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here we used psilocybin, a classic psychedelic found
Jonathan P Roiser et al.
Current biology : CB, 22(7), R231-R233 (2012-04-14)
Two recent studies report changes in human brain responses after exposure to psilocybin, the active ingredient of hallucinogenic mushrooms. Psilocybin increased sensory cortex responses during emotional recollection, but decreased resting-state blood flow in prefrontal cortex, with potential implications for treating depression.
Erich Studerus et al.
PloS one, 7(2), e30800-e30800 (2012-03-01)
Responses to hallucinogenic drugs, such as psilocybin, are believed to be critically dependent on the user's personality, current mood state, drug pre-experiences, expectancies, and social and environmental variables. However, little is known about the order of importance of these variables
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