N193

1-Naphthylacetyl spermine trihydrochloride

≥95% (HPLC), Ca2+ permeable AMPA receptor channel blocker, powder

• Sinonimo/i: NASPM trihydrochloride
• Formula empirica (notazione di Hill): C₂₂H₃₄N₄O · 3HCl
• Numero CAS: 1049731-36-3
• Peso molecolare: 479.91
• UNSPSC Code: 12352200
• PubChem Substance ID: 24897539
• NACRES: NA.77
• MDL number: MFCD01321052
• Assay: ≥95% (HPLC)
• Form: powder
• Storage condition: desiccated, protect from light

Proprietà

• Nome del prodotto: 1-Naphthylacetyl spermine trihydrochloride,
• assay: ≥95% (HPLC)
• Quality Segment: 100
• form: powder
• storage condition: desiccated, protect from light
• color: white
• solubility: H₂O: ≥20 mg/mL
• SMILES string: Cl.Cl.Cl.NCCCNCCCCNCCCNC(=O)Cc1cccc2ccccc12
• InChI: 1S/C22H34N4O.3ClH/c23-12-6-15-24-13-3-4-14-25-16-7-17-26-22(27)18-20-10-5-9-19-8-1-2-11-21(19)20;;;/h1-2,5,8-11,24-25H,3-4,6-7,12-18,23H2,(H,26,27);3*1H
• InChI key: JNEOJAUJWOPWJS-UHFFFAOYSA-N

Descrizione

Application

1-Naphthylacetyl spermine trihydrochloride has been used for the inhibition of calcium-permeable AMPAR (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor). It has also been used to study the involvement of AMPAR in biphasic activation of stress-activated protein kinase/extracellular signal-regulated kinase-1.

Biochem/physiol Actions

Blocks Ca²⁺ permeable AMPA receptor channels.

Other Notes

Synthetic analog of Joro spider toxin.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)