M9948
Mirin
≥98% (HPLC), Mre11–Rad50–Nbs1 complex inhibitor, powder
Sinonimo/i:
5-(4-Hydroxybenzylidene)-2-iminothiazolidin-4-one
Scegli un formato
| Voi/SKU | Disponibilità | Prezzo |
|---|---|---|
5 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 130.00 |
25 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 332.00 |
Informazioni su questo articolo
Nome del prodotto
Mirin, ≥98% (HPLC), powder
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
red to orange
solubility
DMSO: >10 mg/mL
storage temp.
2-8°C
SMILES string
NC1=NC(=O)C(\S1)=C\c2ccc(O)cc2
InChI
1S/C10H8N2O2S/c11-10-12-9(14)8(15-10)5-6-1-3-7(13)4-2-6/h1-5,13H,(H2,11,12,14)/b8-5-
InChI key
YBHQCJILTOVLHD-YVMONPNESA-N
Gene Information
human ... MRE11A(4361)
Application
- as a small molecule inhibitor of meiotic recombination 11 (MRE11), in the pre-treatment of HCT116 wildtype cells before irradiation
- as Mre11 inhibitior in BSC-1 cells infected with simian virus 40
- in the pre-treatment of W12E cells for quantification of human papilloma virus (HPV) episome levels and to potentiate the effect of polyamide-25 (PA-25)
Biochem/physiol Actions
1 of 1
Questo articolo | |||
|---|---|---|---|
| description ≥98% (HPLC), powder | description The MRN-ATM Pathway Inhibitor, Mirin, also referenced under CAS 299953-00-7, controls the biological activity of Mre11, component of the MRN (Mre11-Rad50-Nbs1) complex. This small molecule/inhibitor is primarily used for Cell Structure applications. | description >97.5% (Pt analysis) | description phyproof® Reference Substance |
| form powder | form powder | form powder | form solid |
| assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay >97.5% (Pt analysis) | assay ≥95.0% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. - |
| storage condition desiccated | storage condition OK to freeze, protect from light | storage condition desiccated | storage condition - |
| solubility DMSO: >10 mg/mL | solubility ethanol: 3 mg/mL, DMSO: 10 mg/mL | solubility DMSO: 2 mg/mL, clear | solubility - |
Classe di stoccaggio
11 - Combustible Solids
Che succede?
WGK 3
Punto di infiammabilità (°F)
Not applicable
Punto di infiammabilità (°C)
Not applicable
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