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M7397

L-(−)-Malic acid

suitable for cell culture, BioReagent, suitable for insect cell culture

Sinonimo/i:

(S)-(−)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid

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Voi/SKUDisponibilitàPrezzo
25 g
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CHF 91.80
100 g
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CHF 158.00
500 g
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CHF 535.00

Informazioni su questo articolo

Formula condensata:
HO2CCH2CH(OH)CO2H
Numero CAS:
Peso molecolare:
134.09
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
EC Number:
202-601-5
Beilstein/REAXYS Number:
1723541
MDL number:
Assay:
≥95% (titration)
Form:
powder

CHF 91.80


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biological source

microbial

Quality Segment

product line

BioReagent

assay

≥95% (titration)

form

powder

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

mp

101-103 °C (lit.)

solubility

water: 100 mg/mL, clear to slightly hazy, colorless

SMILES string

O[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

BJEPYKJPYRNKOW-REOHCLBHSA-N

General description

Malic acid is used as a component of insect tissue culture. It is also useful as an acidulant in soft drinks, jams, fruit and vegetable juices.

Application

Malic acid has been used:
  • to induce basal respiration in mitochondrial cell culture
  • to measure the mitochondrial ETC (electron transport chain) activity
  • as a component of mitochondrial substrate stock

Biochem/physiol Actions

Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.

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Questo articolo
M100009172112577
L-(−)-Malic acid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

09172

L-(−)-Malic acid

description

suitable for cell culture, BioReagent, suitable for insect cell culture

description

≥95% (titration)

description

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

description

97%, optical purity ee: 99% (GLC)

assay

≥95% (titration)

assay

≥95% (titration)

assay

-

assay

97%

Quality Level

200

Quality Level

300

Quality Level

300

Quality Level

200

form

powder

form

powder

form

-

form

powder

solubility

water: 100 mg/mL, clear to slightly hazy, colorless

solubility

water: 100 mg/mL, clear to very slightly hazy, colorless

solubility

-

solubility

-

mp

101-103 °C (lit.)

mp

101-103 °C ((lit.)), 101-103 °C (lit.)

mp

101-103 °C (lit.)

mp

101-103 °C (lit.)

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

-

technique(s)

gas chromatography (GC): suitable

technique(s)

-


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signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Questions

  1. What is the quality level of this product? (I would like to use it as an ingredient in a medium to cultivate cells to be used as starting material for a pharmaceutical product, do you have other suggestions?)

    1 answer
    1. This product is an MQ Level 200 and suitable for research use only. It would not be suitable for the production of a pharmaceutical product. Currently, there is no L-(?)-Malic acid offered that is suitable for this application.

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