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Documenti fondamentali

M6502

Sigma-Aldrich

6-Methylpurine

≥99%

Sinonimo/i:

MeP

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100 MG
CHF 91.00
250 MG
CHF 175.00

CHF 91.00


Spedizione prevista il01 giugno 2025



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Cambia visualizzazione
100 MG
CHF 91.00
250 MG
CHF 175.00

About This Item

Formula empirica (notazione di Hill):
C6H6N4
Numero CAS:
Peso molecolare:
134.14
Numero CE:
Numero MDL:
Codice UNSPSC:
41106305
ID PubChem:
NACRES:
NA.51

CHF 91.00


Spedizione prevista il01 giugno 2025


Origine biologica

synthetic (organic)

Saggio

≥99%

Stato

powder

Punto di fusione

237-238 °C (lit.)

Solubilità

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

Temperatura di conservazione

−20°C

Stringa SMILE

Cc1ncnc2[nH]cnc12

InChI

1S/C6H6N4/c1-4-5-6(9-2-7-4)10-3-8-5/h2-3H,1H3,(H,7,8,9,10)
SYMHUEFSSMBHJA-UHFFFAOYSA-N

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Applicazioni

6-Methylpurine (MeP) is a toxic adenine analog used as a bisubstrate inhibitor of enzymes that bind adenosyl moieties and which may become phosphorylated to levels that inhibit RNA and protein synthesis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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H Ohgaki et al.
Journal of cancer research and clinical oncology, 117(1), 13-18 (1991-01-01)
The formation of O6-methyldeoxyguanosine (O6-MedGuo) was determined by an immuno-slot-blot assay in DNA of various tissues of F344 rats exposed to N-methyl-N-nitrosourea (MNU) in the drinking water at 400 ppm for 2 weeks. Although the pyloric region of the glandular
Juan Li et al.
Water research, 135, 75-84 (2018-02-20)
This work investigated impacts of iodide (I-) on the transformation of the widely used phenolic preservative methylparaben (MeP) as well as 11 other phenolic compounds by potassium permanganate (KMnO4). It was found that KMnO4 showed a low reactivity towards MeP
Norma Susana Pano-Farias et al.
Journal of food and drug analysis, 25(3), 501-509 (2017-09-16)
In this paper a method of using the "quick, easy, cheap, effective, rugged, and safe" (QuEChERS) extraction and gas chromatography coupled to mass spectrometry detection (GC-MS) was developed for the analysis of five frequently applied pesticides in papaya and avocado.
G Klobus et al.
Plant physiology, 87, 878-882 (1988-01-01)
The nature of the injury and recovery of nitrate uptake (net uptake) from NaCl stress in young barley (Hordeum vulgare L, var CM 72) seedlings was investigated. Nitrate uptake was inhibited rapidly by NaCl, within 1 minute after exposure to
B W Hughes et al.
The Journal of biological chemistry, 273(4), 2322-2328 (1998-01-27)
Expression of Escherichia coli purine nucleoside phosphorylase (PNP) activates prodrugs and kills entire populations of mammalian cells, even when as few as 1% of the cells express this gene. This phenomenon of bystander killing has been previously investigated for herpes

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