This product may be stored at room temperature in the powdered format. The solution stability of this material has not been determined. However, various external sources indicate that prepared solutions are stable up to 1 month when stored tightly sealed in aliquots at -20°C. This information has not been validated.
M5441
Mibefradil dihydrochloride hydrate
≥98% (HPLC), powder, T-type Ca²⁺ channel blocker
Sinonimo/i:
(1S,2S)-2-[2[[3-(2-Benzimidazolyl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate dihydrochloride hydrate, Ro 40-5967 hydrate
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5 MG
CHF 155.00
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CHF 618.00
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5 MG
CHF 155.00
25 MG
CHF 618.00
About This Item
Formula empirica (notazione di Hill):
C29H38FN3O3 · 2HCl · xH2O
Numero CAS:
Peso molecolare:
568.55 (anhydrous basis)
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77
Prodotti consigliati
Nome del prodotto
Mibefradil dihydrochloride hydrate, ≥98% (HPLC), powder
Saggio
≥98% (HPLC)
Stato
powder
Condizioni di stoccaggio
desiccated
Colore
white
Solubilità
H2O: soluble >20 mg/mL
absolute ethanol: insoluble
Ideatore
Roche
Stringa SMILE
O.Cl.Cl.COCC(=O)O[C@]3(CCN(C)CCCc1nc2ccccc2[nH]1)CCc4cc(F)ccc4[C@@H]3C(C)C
InChI
1S/C29H38FN3O3.2ClH.H2O/c1-20(2)28-23-12-11-22(30)18-21(23)13-14-29(28,36-27(34)19-35-4)15-17-33(3)16-7-10-26-31-24-8-5-6-9-25(24)32-26;;;/h5-6,8-9,11-12,18,20,28H,7,10,13-17,19H2,1-4H3,(H,31,32);2*1H;1H2/t28-,29-;;;/m0.../s1
IZSWBBGKLWFDOC-YKXHUFBBSA-N
Applicazioni
Azioni biochim/fisiol
Mibefradil is a tetralol derivative and nondihydropyridine calcium channel blocker. It blocks long-type (L-type) calcium channels.[3][4] It blocks mildly the Purkinje-type (P-type) calcium channels in Purkinje neurons.[5]
Ro 40-5967 is a T-type Ca2+ channel blocker; antihypertensive.
Caratteristiche e vantaggi
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Oral
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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At what temperature should the compound be stored in powder for? And at what temperature in Solution?
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