Each batch release of this product has been tested for solubility at 50 mg/mL in ethanol. Turbidity observations are recorded as "clear to slightly hazy," and specific results for each batch are indicated in the Certificate of Analysis.
M4145
Minoxidil
≥99% (TLC), powder, potassium channel activator
1 of 2 reviewers received a sample product or took part in a promotion
Sinonimo/i:
6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide, 6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide
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Cambia visualizzazione
| Voi/SKU | Disponibilità | Prezzo |
|---|---|---|
25 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 96.50 |
100 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 187.00 |
250 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 481.00 |
500 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 851.00 |
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C9H15N5O
Numero CAS:
Peso molecolare:
209.25
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
253-874-2
MDL number:
Assay:
≥99% (TLC)
Servizio Tecnico
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Permettici di aiutartiNome del prodotto
Minoxidil, ≥99% (TLC)
Quality Segment
assay
≥99% (TLC)
mp
272-274 °C (dec.) (lit.)
originator
Johnson & Johnson
SMILES string
NC1=CC(=NC(=N)N1O)N2CCCCC2
InChI
1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
InChI key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
Gene Information
human ... KCNJ1(3758)
Application
Minoxidil has been used as test drug:
- in dermal papilla spheroid model, to study the effect of hair regeneration
- administered orally to experimental rats, in the approach to identify biomarkers of drug induced vascular injury
- administered via oral gavage to nonhuman primate model in order to study its effect on tilt responses
Biochem/physiol Actions
Minoxidil is originally used to treat hypertension, which also induces hypertrichosis. It is considered as a potent drug for treating androgenetic alopecia.
Activates ATP-activated K+ channels; vasodilator; slow or stop hair loss and promote hair regrowth.
Features and Benefits
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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Questo articolo | |||
|---|---|---|---|
| description ≥99% (TLC) | description European Pharmacopoeia (EP) Reference Standard | description British Pharmacopoeia (BP) Reference Standard | description European Pharmacopoeia (EP) Reference Standard |
| assay ≥99% (TLC) | assay - | assay - | assay - |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level - |
| originator Johnson & Johnson | originator - | originator - | originator - |
| Gene Information human ... KCNJ1(3758) | Gene Information - | Gene Information - | Gene Information - |
| mp 272-274 °C (dec.) (lit.) | mp 272-274 °C (dec.) (lit.) | mp 272-274 °C (dec.) (lit.) | mp 272-274 °C (dec.) (lit.) |
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Parola di avvertenza
Warning
Codici di pericolo
Avvertenze di sicurezza
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Classe di stoccaggio
11 - Combustible Solids
Che succede?
WGK 3
DPI (dispositivi di protezione individuale)
dust mask type N95 (US), Eyeshields, Gloves
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Accordingtobibliography,the solubility of minoxidil(CAS 38304-91-5)is 1-7 mg/ml in EtOH.However,you state that the solubility ofSIGMAminoxidil isCLEARCOLORLESS TO VERYSLIGHTLYHAZY FAINT YELLOW SOLUTION AT 50 MG PLUS 1 ML OF EtOH in the specificationsheet.
1 answer-
Helpful?
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Hi، Is the unit of measurement correctly written in milligrams? Shouldn't it have been written gram?
1 answer-
Yes, the milligram quantities listed for the package sizes is correct. The packaged product is not available in gram quantities.
Helpful?
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