M2295
Myelin Basic Protein from guinea pig brain
≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain
Sinonimo/i:
MBP
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Prodotti consigliati
Origine biologica
guinea pig brain
Livello qualitativo
Saggio
≥80% (SDS-PAGE)
Forma fisica
lyophilized powder
tecniche
cell based assay: suitable
N° accesso UniProt
applicazioni
cell analysis
Temperatura di conservazione
−20°C
Informazioni sul gene
guinea pig ... MBP(100731253)
Descrizione generale
Myelin Basic Protein (MBP) expressed in guinea pig brain contains 167 amino acids and has a molecular weight of 18,256Da.
Research area: Cell SignallingMyelin basic protein (MBP) is an important constituent of the myelin sheath of CNS (central nervous system). It is an auto-immunogen.
Applicazioni
Myelin Basic Protein fromguinea pig brain has been used as a kinase substrate: to analyse in vitrokinase activity, in protein phosphorylation analysis, in ATG1 kinaseassay
Azioni biochim/fisiol
Mutation of the myelin basic protein gene induces dysmyelination; used to induce experimental allergic encephalomyelitis.
Myelin basic protein (MBP) plays a vital role in formation of myelin sheath and is associated with the various neurological disorders. MBP function as an antigenic target in autoimmune disease experimental allergic encephalomyelitis (EAE). MBP plays an essential role in cytoskeletal turnover and membrane extension. Additionally, it is also involved in Fyn-mediated signaling pathways, sequestration of phosphoinositides and regulation of calcium homoeostasis. MBP functions as an in vitro substrate for mitogen-activated protein kinase (MAP) kinase and aids in the purification and functional studies of enzyme.
Qualità
May contain traces of urea-glycine buffer salts.
Principio
Used as a kinase substrate.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I clienti hanno visto anche
Glucagon-Like Peptide-1 Analog, Liraglutide, Delays Onset of Experimental Autoimmune Encephalitis in Lewis Rats
Della VB, et al.
Frontiers in Pharmacology, 7, 787-802 (2016)
Metallic gold slows disease progression, reduces cell death and induces astrogliosis while simultaneously increasing stem cell responses in an EAE rat model of multiple sclerosis
Pedersen DS, et al.
Histochemistry and Cell Biology, 138(5), 787-802 (2012)
Sequence of guinea pig myelin basic protein.
Deibler GE
Journal of Neurochemistry, 43(1), 100-105 (1984)
J A Last et al.
Toxicology, 39(3), 247-257 (1986-06-01)
A synergistic interaction, as defined by biochemical and morphological criteria, between ozone (or NO2) and respirable aerosols of ammonium sulfate or sulfuric acid has been described previously. Experiments in the present paper show that it is the acidity, not the
Karine Thibault et al.
European journal of pain (London, England), 15(3), 231-231 (2010-09-11)
Multiple sclerosis is a chronic inflammatory demyelinating disease, associated, in 50-80% of patients, with persistent pain. While the type of pain that affects these patients is being more documented, the mechanisms underlying this pathology are still poorly understood and animal
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.