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M0814

Sigma-Aldrich

R(−)-Me5 hydriodide

solid

Sinonimo/i:

1-(2,6-Dimethylphenoxy)-3-methyl-2-butanamine hydriodide

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About This Item

Formula empirica (notazione di Hill):
C13H21NO · HI
Peso molecolare:
335.22
Numero MDL:
MFCD03452961
Codice UNSPSC:
12352200
ID PubChem:
24278531

Stato

solid

Colore

white

Solubilità

H2O: 22 mg/mL

Stringa SMILE

I[H].CC(C)C(N)COc1c(C)cccc1C

InChI

1S/C13H21NO.HI/c1-9(2)12(14)8-15-13-10(3)6-5-7-11(13)4;/h5-7,9,12H,8,14H2,1-4H3;1H
AQLAXCGHPBMFIJ-UHFFFAOYSA-N

Informazioni sul gene

human ... SCN2A(6326)

Applicazioni

May be used as a sodium channel blocker in sketetal muscle.

Azioni biochim/fisiol

Potent sodium channel antagonist.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
111K4707

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M Takanashi et al.
Gene therapy, 16(8), 982-989 (2009-05-29)
Recent advances of biotechnology have laid the groundwork for potent and specific molecular-targeting therapies including RNA interference. The largest remaining hurdle for widespread use of this technology in skin is an effective delivery system. Here, we demonstrate an effective topical
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On the basis of the information about drug receptor on voltage-gated sodium channels, mexiletine (Mex) analogs with substitutions at either the asymmetric carbon atom or the aromatic ring were synthesized as pure enantiomers. The compounds were tested in vitro for
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Pulmonary surfactant is a complex mixture of phospholipids and four surfactant-associated proteins (SP-A, SP-B, SP-C and SP-D). The biological functions of SP-A and SP-D are primarily twofold, namely surfactant homeostasis and host defense. The hydrophobic surfactant proteins, SP-B and SP-C
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To evaluate MGMT promoter hypermethylation as prognostic factor in a retrospective study of 104 cases of glioblastoma multiforme (GBM). The O(6)-methylguanine-DNA methyltransferase (MGMT) status was evaluated by methylation-specific PCR (MSP), immunohistochemistry and Western blotting analysis in formalin-fixed paraffin-embedded surgical samples.
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