L4641
Lipopolysaccharides from Salmonella enterica serotype minnesota
γ-irradiated, BioXtra, suitable for cell culture
Sinonimo/i:
LPS
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About This Item
Prodotti consigliati
Origine biologica
Salmonella enterica (Serotype minnesota)
Sterilità
γ-irradiated
Nome Commerciale
BioXtra
Stato
lyophilized powder
Purificato mediante
gel-filtration chromatography
tecniche
cell culture | mammalian: suitable
Impurezze
<1% Protein (Lowry)
Temperatura di conservazione
2-8°C
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Descrizione generale
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Applicazioni
Lipopolysaccharides from Salmonella enterica serotype Minnesota are used in cell culture and cell binding applications. LPS was used to elicit the activation of NF-κB pathway in human intestinal epithelial cells[1] and mouse dendritic cells.[2] It was used to study the immune responses following autologous blood donation.[3]
Azioni biochim/fisiol
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Altre note
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
13 - Non Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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I clienti hanno visto anche
R Karger et al.
Transfusion medicine (Oxford, England), 17(1), 45-53 (2007-02-03)
Preoperative autologous blood donation (PABD) has been shown to decrease natural killer (NK) cell function in cancer patients, raising concerns about an increased cancer recurrence risk owing to PABD. It is unclear whether PABD leads to other immunomodulatory effects that
Zsolt Czimmerer et al.
Immunity, 48(1), 75-90 (2018-01-19)
The molecular basis of signal-dependent transcriptional activation has been extensively studied in macrophage polarization, but our understanding remains limited regarding the molecular determinants of repression. Here we show that IL-4-activated STAT6 transcription factor is required for the direct transcriptional repression
Sumit Bhattacharyya et al.
American journal of physiology. Gastrointestinal and liver physiology, 293(2), G429-G437 (2007-06-02)
Lipopolysaccharide (LPS) is recognized as an inducer of the inflammatory response associated with gram-negative sepsis and systemic inflammatory response syndrome. LPS induction proceeds through Toll-like receptor (TLR) in immune cells and intestinal epithelial cells (IEC). This report presents the first
Michele Ferrara et al.
Frontiers in immunology, 11, 1122-1122 (2020-07-17)
Acute inflammation is a complex biological response of tissues to harmful stimuli, such as pathogens or cell damage, and is essential for immune defense and proper healing. However, unresolved inflammation can lead to chronic disorders, including cancer and fibrosis. The
Kendra Speirs et al.
Journal of immunology (Baltimore, Md. : 1950), 172(2), 752-756 (2004-01-07)
RelB, a member of the NF-kappaB family of transcription factors, is essential for dendritic cell (DC) maturation. Recent findings indicate that RelB is exclusively regulated through its interaction with cytoplasmic NF-kappaB2/p100. The studies presented in this report show that DCs
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