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L4263

Sigma-Aldrich

Sodium DL-lactate solution

BioReagent, syrup, 60 % (w/w), synthetic, suitable for cell culture

Sinonimo/i:

DL-Lactic acid sodium salt

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About This Item

Formula condensata:
CH3CH(OH)COONa
Numero CAS:
Peso molecolare:
112.06
Beilstein:
4332999
Numero CE:
Numero MDL:
Codice UNSPSC:
12352207
ID PubChem:
NACRES:
NA.75

Origine biologica

synthetic

Nome Commerciale

BioReagent

Forma fisica

syrup

Concentrazione

27-33% (enzymatic)
60 % (w/w)

tecniche

cell culture | mammalian: suitable

Temperatura di conservazione

2-8°C

Stringa SMILE

[Na+].CC(O)C([O-])=O

InChI

1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
NGSFWBMYFKHRBD-UHFFFAOYSA-M

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Descrizione generale

Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). Lactate is one of the main components of Ringer′s lactate or lactated Ringer′s solution.

Applicazioni

Sodium DL-lactate solution has been used:
  • as a component in DMEM-B to prepare Dulbecco modified Eagle medium (DMEM)-C medium to evaluate the effect of medium composition on in vitro spermatogonial stem cells (SSCs) maintenance
  • as a supplement in Dulbecco′s modified Eagle′s medium-nutrient mixture F12 to obtain conditioned media of testicular macrophages
  • as a component in non-capacitation medium and TALP medium for sperm preparation and in vitro fertilization
  • in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffered synthetic oviduct fluid (SOF) media for oocyte preservation

Azioni biochim/fisiol

Lactic acid is produced by lactic acid bacteria (LAB) during carbohydrate fermentation. Different microorganism synthesize different forms of lactic acid such as L(+), D(-) or DL (racemic mixture). It is preferred in food processing and preservation due to its antimicrobial property. Lactic acid is useful as a flavoring and acidifying agent.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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Oocyte transport: developmental competence of bovine oocytes arrested at germinal vesicle stage by cycloheximide under air
<BIG>Hashimoto S, et al.</BIG>
Journal of Reproduction and Development, 49, 61-66 (2003)
<BIG>Ameen SM, et al.</BIG>
Lactic Acid in the Food Industry, 20-20 (2017)
Maintenance of mouse male germ line stem cells in vitro
<BIG>Nagano M, et al.</BIG>
Biology of Reproduction, 86, 2207-2214 (2003)
Tumour necrosis factor-alpha released by testicular macrophages induces apoptosis of germ cells in autoimmune orchitis
<BIG>Theas MS, et al.</BIG>
Human Reproduction, 23, 1865-1872 (2008)
Wenqian Yuan et al.
Food microbiology, 30(2), 448-452 (2012-03-01)
The aim of the present study was to determine the survival of Salmonella Typhimurium adapted with sodium lactate (NaL), potassium lactate/sodium acetate mixture (KL/NaA) or sodium acetate (NaA) in simulated gastric fluid (SGF) and during heat treatment. NaL-, KL/NaA- and

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