J3205

JNJ-1661010

≥98% (HPLC)

• Formula empirica (notazione di Hill): C₁₉H₁₉N₅OS
• Peso molecolare: 365.45
• Numero MDL: MFCD00209157
• Codice UNSPSC: 12352200
• ID PubChem: 329815405
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Stato: solid
• Solubilità: DMSO: ≥28 mg/mL
• Ideatore: Johnson & Johnson
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O=C(Nc1ccccc1)N2CCN(CC2)c3nc(ns3)-c4ccccc4
• InChI: 1S/C19H19N5OS/c25-18(20-16-9-5-2-6-10-16)23-11-13-24(14-12-23)19-21-17(22-26-19)15-7-3-1-4-8-15/h1-10H,11-14H2,(H,20,25); BHBOSTKQCZEAJM-UHFFFAOYSA-N

Descrizione

Azioni biochim/fisiol

JNJ-1661010 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with >100-fold preferentially selective for FAAH-1 over FAAH-2. FAAH in an integral membrane enzyme within the amidase-signature family. It catalyzes the hydrolysis of several endogenous biologically active lipids and involves in a variety of physiological and pathological processes, including synaptic regulation, regulation of sleep and feeding, locomotor activity, pain and inflammation.

JNJ-1661010 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor.

Caratteristiche e vantaggi

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable