GW22348F

Anti-LXN antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: chicken
• Livello qualitativo: 200
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Stato: buffered aqueous solution
• Reattività contro le specie: human, mouse, rat
• Produttore/marchio commerciale: Genway 15-288-22348F
• tecniche: indirect ELISA: suitable; western blot: suitable
• N° accesso NCBI: NP_064554.1
• N° accesso UniProt: Q9BS40
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... LXN(56925)

Descrizione

Descrizione generale

LXN (latexin) is the human homologue of endogenous inhibitor of carboxypeptidase A found in rat. It was initially recognized as a neural marker in developing mammalian brain, of the lateral neocortex.[1] This protein is composed of 222 amino acids. An α-helix links two subdomains that comprise the protein. It has high structural homology to TIG1 (tazarotene-induced gene 1).

Immunogeno

Immunogen Sequence: GI # 9910396, sequence 1-222

Recombinant latexin protein

Applicazioni

Anti-LXN antibody produced in chicken is suitable for indirect ELISA and western blotting.

Azioni biochim/fisiol

Latexin (LXN) is a negative regulator of hematopoietic stem cell and may exert its tumor-suppressive function by altering the stem cell-like properties of melanoma cells.[1] Its expression is reduced in human gastric cancers compared with their normal control tissues. LXN expression may have involvement in tumor suppression. It may have clinical efficacy in the treatment of malignancies.

Stato fisico

Solution in phosphate buffered saline containing 0.02% sodium azide.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)