G5146

D-(+)-Glucosio

Hybri-Max^™, powder, BioReagent, suitable for hybridoma

• Sinonimo/i: Destrosio
• Formula empirica (notazione di Hill): C₆H₁₂O₆
• Numero CAS: 50-99-7
• Peso molecolare: 180.16
• Beilstein: 1724615
• Numero CE: 200-075-1
• Numero MDL: MFCD00063774
• Codice UNSPSC: 12352201
• ID PubChem: 24895199
• NACRES: NA.75

Proprietà

• Origine biologica: maize
• Grado: Hybri-Max^™
• Nome Commerciale: BioReagent
• Saggio: ≥99.5%
• Forma fisica: powder
• tecniche: cell culture | hybridoma: suitable
• Impurezze: endotoxin, tested
• Punto di fusione: 150-152 °C (lit.)
• Solubilità: H₂O: 2g + 15 mL (Tested)
• Stringa SMILE: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1; WQZGKKKJIJFFOK-DVKNGEFBSA-N
• Informazioni sul gene: human ... PYGM(5837)

Descrizione

Descrizione generale

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively. The PYGM gene is mapped to human chromosome 11q13.1.

Applicazioni

D-(+)-Glucose has been used in cell engineering. It has also been used to perform oral glucose tolerance test.

Azioni biochim/fisiol

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia. Mutation in PYGM leads to McArdle disease, a glycogen storage disorder. The PYGM gene is significantly associated with energy production.

Nota sulla preparazione

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Note legali

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)